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Reacciones adversas ZINC SULFATO despus de una administracin prolongada, el sulfato de zinc puede provocar deficiencia de cobre
41 In detail, the elevated extracellular ATP induced by SD stress stimulates P2 7 R and down-regulates the expression of 5-HT 2B R by suppressing the activation of AKT, which inhibits the phosphorylation of FoxO3a and promotes its transportation into the nucleus, the reduced 5-HT 2B R alleviates the inhibition of STAT3 to cPLA 2 , the activated cPLA 2 further increases the release of AA and PGE2, these indicators have high relationship with the depressive-like behaviors, because in P2X 7 R knockout mice, the above changes of these indicators and behavioral performance are all eliminated
PC-specific transfer protein and non-specific lipid transfer proteins may play a role, but animal studies suggest that neither accounts for the entirety of PC movement (Vance 2014)
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